null

SMILES: CCc1nc(N)nc(N)c1-c1ccc(cc1)-c1cn(CCCCCC(=O)NO)nn1

InChI Key: InChIKey=QCVCOCOMJLADHP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50545001   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50545001 (CHEMBL4649487) Show SMILES CCc1nc(N)nc(N)c1-c1ccc(cc1)-c1cn(CCCCCC(=O)NO)nn1 Show InChI InChI=1S/C20H26N8O2/c1-2-15-18(19(21)24-20(22)23-15)14-9-7-13(8-10-14)16-12-28(27-25-16)11-5-3-4-6-17(29)26-30/h7-10,12,30H,2-6,11H2,1H3,(H,26,29)(H4,21,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 using fluorogenic HDAC substrate preincubated for 30 mins followed by substrate addition and measured after 15 ...				Bioorg Med Chem 28: (2020)
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50545001 (CHEMBL4649487) Show SMILES CCc1nc(N)nc(N)c1-c1ccc(cc1)-c1cn(CCCCCC(=O)NO)nn1 Show InChI InChI=1S/C20H26N8O2/c1-2-15-18(19(21)24-20(22)23-15)14-9-7-13(8-10-14)16-12-28(27-25-16)11-5-3-4-6-17(29)26-30/h7-10,12,30H,2-6,11H2,1H3,(H,26,29)(H4,21,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC8 using fluorogenic HDAC substrate class 2A preincubated for 30 mins followed by substrate addition and measured ...				Bioorg Med Chem 28: (2020)
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50545001 (CHEMBL4649487) Show SMILES CCc1nc(N)nc(N)c1-c1ccc(cc1)-c1cn(CCCCCC(=O)NO)nn1 Show InChI InChI=1S/C20H26N8O2/c1-2-15-18(19(21)24-20(22)23-15)14-9-7-13(8-10-14)16-12-28(27-25-16)11-5-3-4-6-17(29)26-30/h7-10,12,30H,2-6,11H2,1H3,(H,26,29)(H4,21,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6 using fluorogenic HDAC substrate 3 preincubated for 30 mins followed by substrate addition and measured after 1...				Bioorg Med Chem 28: (2020)
					More data for this Ligand-Target Pair