BDBM50545100 CHEMBL1990482

SMILES: NC(=O)c1cccc2[nH]c(nc12)-c1ccncc1

InChI Key: InChIKey=CZIGMBNEFWBEMD-UHFFFAOYSA-N

Data: 5 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50545100   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase N2 (Homo sapiens (Human))	BDBM50545100 (CHEMBL1990482) Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccncc1 Show InChI InChI=1S/C13H10N4O/c14-12(18)9-2-1-3-10-11(9)17-13(16-10)8-4-6-15-7-5-8/h1-7H,(H2,14,18)(H,16,17)	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Sussex Curated by ChEMBL					Assay Description Displacement of tracer from PKN2 (unknown origin) by TR-FRET assay				Bioorg Med Chem Lett 30: (2020)
					More data for this Ligand-Target Pair
Protein kinase N2 (Homo sapiens (Human))	BDBM50545100 (CHEMBL1990482) Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccncc1 Show InChI InChI=1S/C13H10N4O/c14-12(18)9-2-1-3-10-11(9)17-13(16-10)8-4-6-15-7-5-8/h1-7H,(H2,14,18)(H,16,17)	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Sussex Curated by ChEMBL					Assay Description Inhibition of His/GST-tagged PKN2 (unknown origin) using biotinylated peptide as substrate measured after 1 hr in presence of [gamma-33P]-ATP by fluo...				Bioorg Med Chem Lett 30: (2020)
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase N1/Transforming protein RhoA (Homo sapiens (Human))	BDBM50545100 (CHEMBL1990482) Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccncc1 Show InChI InChI=1S/C13H10N4O/c14-12(18)9-2-1-3-10-11(9)17-13(16-10)8-4-6-15-7-5-8/h1-7H,(H2,14,18)(H,16,17)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Sussex Curated by ChEMBL					Assay Description Displacement of tracer from PKN1 (unknown origin) by TR-FRET assay				Bioorg Med Chem Lett 30: (2020)
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1/CLK4 (Homo sapiens (Human))	BDBM50545100 (CHEMBL1990482) Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccncc1 Show InChI InChI=1S/C13H10N4O/c14-12(18)9-2-1-3-10-11(9)17-13(16-10)8-4-6-15-7-5-8/h1-7H,(H2,14,18)(H,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	<1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Sussex Curated by ChEMBL					Assay Description Inhibition of His/GST-tagged CLK4 (unknown origin) using biotinylated peptide as substrate measured after 1 hr in presence of [gamma-33P]-ATP by fluo...				Bioorg Med Chem Lett 30: (2020)
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase N1/Transforming protein RhoA (Homo sapiens (Human))	BDBM50545100 (CHEMBL1990482) Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccncc1 Show InChI InChI=1S/C13H10N4O/c14-12(18)9-2-1-3-10-11(9)17-13(16-10)8-4-6-15-7-5-8/h1-7H,(H2,14,18)(H,16,17)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	<1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Sussex Curated by ChEMBL					Assay Description Inhibition of His/GST-tagged PKN1 (unknown origin) using biotinylated peptide as substrate measured after 1 hr in presence of [gamma-33P]-ATP by fluo...				Bioorg Med Chem Lett 30: (2020)
					More data for this Ligand-Target Pair
Protein kinase N2 (Homo sapiens (Human))	BDBM50545100 (CHEMBL1990482) Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccncc1 Show InChI InChI=1S/C13H10N4O/c14-12(18)9-2-1-3-10-11(9)17-13(16-10)8-4-6-15-7-5-8/h1-7H,(H2,14,18)(H,16,17)	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
University of Sussex Curated by ChEMBL					Assay Description Displacement of tracer from PKN2 (unknown origin) by TR-FRET assay				Bioorg Med Chem Lett 30: (2020)
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase N1/Transforming protein RhoA (Homo sapiens (Human))	BDBM50545100 (CHEMBL1990482) Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccncc1 Show InChI InChI=1S/C13H10N4O/c14-12(18)9-2-1-3-10-11(9)17-13(16-10)8-4-6-15-7-5-8/h1-7H,(H2,14,18)(H,16,17)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Sussex Curated by ChEMBL					Assay Description Displacement of tracer from PKN1 (unknown origin) by TR-FRET assay				Bioorg Med Chem Lett 30: (2020)
					More data for this Ligand-Target Pair