BDBM50545113 CHEMBL4647033

SMILES: NC(=O)c1cc(Br)cc2[nH]c(nc12)-c1ccncc1

InChI Key: InChIKey=MFMOSBDEOQIGBY-UHFFFAOYSA-N

Data: 2 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50545113   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase N2 (Homo sapiens (Human))	BDBM50545113 (CHEMBL4647033) Show SMILES NC(=O)c1cc(Br)cc2[nH]c(nc12)-c1ccncc1 Show InChI InChI=1S/C13H9BrN4O/c14-8-5-9(12(15)19)11-10(6-8)17-13(18-11)7-1-3-16-4-2-7/h1-6H,(H2,15,19)(H,17,18)	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Sussex Curated by ChEMBL					Assay Description Displacement of tracer from PKN2 (unknown origin) by TR-FRET assay				Bioorg Med Chem Lett 30: (2020)
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase N1/Transforming protein RhoA (Homo sapiens (Human))	BDBM50545113 (CHEMBL4647033) Show SMILES NC(=O)c1cc(Br)cc2[nH]c(nc12)-c1ccncc1 Show InChI InChI=1S/C13H9BrN4O/c14-8-5-9(12(15)19)11-10(6-8)17-13(18-11)7-1-3-16-4-2-7/h1-6H,(H2,15,19)(H,17,18)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	2.19E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Sussex Curated by ChEMBL					Assay Description Displacement of tracer from PKN1 (unknown origin) by TR-FRET assay				Bioorg Med Chem Lett 30: (2020)
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase N1/Transforming protein RhoA (Homo sapiens (Human))	BDBM50545113 (CHEMBL4647033) Show SMILES NC(=O)c1cc(Br)cc2[nH]c(nc12)-c1ccncc1 Show InChI InChI=1S/C13H9BrN4O/c14-8-5-9(12(15)19)11-10(6-8)17-13(18-11)7-1-3-16-4-2-7/h1-6H,(H2,15,19)(H,17,18)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	4.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Sussex Curated by ChEMBL					Assay Description Displacement of tracer from PKN1 (unknown origin) by TR-FRET assay				Bioorg Med Chem Lett 30: (2020)
					More data for this Ligand-Target Pair
Protein kinase N2 (Homo sapiens (Human))	BDBM50545113 (CHEMBL4647033) Show SMILES NC(=O)c1cc(Br)cc2[nH]c(nc12)-c1ccncc1 Show InChI InChI=1S/C13H9BrN4O/c14-8-5-9(12(15)19)11-10(6-8)17-13(18-11)7-1-3-16-4-2-7/h1-6H,(H2,15,19)(H,17,18)	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
University of Sussex Curated by ChEMBL					Assay Description Displacement of tracer from PKN2 (unknown origin) by TR-FRET assay				Bioorg Med Chem Lett 30: (2020)
					More data for this Ligand-Target Pair