null
SMILES: O[C@@H]1[C@@H](COP(O)(=O)CP(O)(O)=O)O[C@H]([C@@H]1O)n1cnc2c(NCc3ccccc3)ncnc12
InChI Key:
PDB links: 1 PDB ID matches this monomer.
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5'-nucleotidase (Homo sapiens (Human)) | BDBM50546335 (CHEMBL4755577) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | PDB Article PubMed | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human recombinant soluble CD73 assessed as inhibition constant by radiometric assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01852 BindingDB Entry DOI: 10.7270/Q2ZS31D5 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
5'-nucleotidase (Homo sapiens (Human)) | BDBM50546335 (CHEMBL4755577) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human CD73 | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00525 BindingDB Entry DOI: 10.7270/Q29W0K29 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |