null

SMILES: Cn1ccc2c(cccc12)-c1nc2c(ccnc2[nH]1)-n1cc(CN2CC[C@@H](O)C2)cn1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50546403   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50546403 (CHEMBL4779316) Show SMILES Cn1ccc2c(cccc12)-c1nc2c(ccnc2[nH]1)-n1cc(CN2CC[C@@H](O)C2)cn1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.480	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SYK (unknown origin)				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127393 BindingDB Entry DOI: 10.7270/Q28W3HVM
					More data for this Ligand-Target Pair
1,3-beta-glucan synthase component GSC2 (Saccharomyces cerevisiae)	BDBM50546403 (CHEMBL4779316) Show SMILES Cn1ccc2c(cccc12)-c1nc2c(ccnc2[nH]1)-n1cc(CN2CC[C@@H](O)C2)cn1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human ERG				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127393 BindingDB Entry DOI: 10.7270/Q28W3HVM
					More data for this Ligand-Target Pair