null
SMILES: ClCC(=O)N1CCc2c(C1)[nH]c1ccccc21
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phospholipid hydroperoxide glutathione peroxidase (Homo sapiens) | BDBM50547227 (CHEMBL4800659) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viability in presence of ferrostatin-1 | Citation and Details Article DOI: 10.1016/j.bmcl.2020.127538 BindingDB Entry DOI: 10.7270/Q2CN77HV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phospholipid hydroperoxide glutathione peroxidase (Homo sapiens) | BDBM50547227 (CHEMBL4800659) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viability | Citation and Details Article DOI: 10.1016/j.bmcl.2020.127538 BindingDB Entry DOI: 10.7270/Q2CN77HV | |||||||||||
More data for this Ligand-Target Pair |