null

SMILES: OC(=O)c1ccc(cc1)-c1csc(n1)N1N=C(\C(=N\Nc2nccs2)C1=O)c1ccccc1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50547481   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator BAX (Homo sapiens (Human))	BDBM50547481 (CHEMBL4777011) Show SMILES OC(=O)c1ccc(cc1)-c1csc(n1)N1N=C(\C(=N\Nc2nccs2)C1=O)c1ccccc1 |c:17| Show InChI	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	704	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to recombinant human full length His-tagged BAX expressed in Escherichia coli BL21 (DE3) cells preincubated for 30 min followed by F...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01454 BindingDB Entry DOI: 10.7270/Q2N301J4
					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50547481 (CHEMBL4777011) Show SMILES OC(=O)c1ccc(cc1)-c1csc(n1)N1N=C(\C(=N\Nc2nccs2)C1=O)c1ccccc1 |c:17| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of HDAC in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC or Boc-Lys (triflouroacetyl)-AMC as substrate preincubated for 5 mins foll...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01454 BindingDB Entry DOI: 10.7270/Q2N301J4
					More data for this Ligand-Target Pair