BindingDB PrimarySearch_ki

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Enter Data

null

SMILES: COc1cc2c(NCCCCCN3CCCC3)nc(nc2cc1OCCN)N1CCCC1

InChI Key:

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50548178
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
N-lysine methyltransferase KMT5A (Homo sapiens (Human))	BDBM50548178 (CHEMBL4793474) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant SETD8 catalytic domain (unknown origin) (232 to 393 residues) expressed in Escherichia coli assessed as reduction in incorp...				Citation and Details BindingDB Entry DOI: 10.7270/Q2988BMD
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
N-lysine methyltransferase KMT5A (Homo sapiens (Human))	BDBM50548178 (CHEMBL4793474) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB PubMed	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to recombinant SETD8 catalytic domain (unknown origin) (232 to 393 residues) expressed in Escherichia coli assessed as dissociation ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2988BMD
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)