null

SMILES: COc1ccc(NC(=O)NC2COc3ccc(F)cc3C2)cc1Cl

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50549330   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50549330 (CHEMBL4751838) Show SMILES COc1ccc(NC(=O)NC2COc3ccc(F)cc3C2)cc1Cl Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Allosteric inhibition of human wild-type full-length MALT1 (329 to 824 residues) protease activity using Ac-Leu-Arg-Ser-Arg Rh110-dPro as substrate p...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01245 BindingDB Entry DOI: 10.7270/Q2S1864D
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50549330 (CHEMBL4751838) Show SMILES COc1ccc(NC(=O)NC2COc3ccc(F)cc3C2)cc1Cl Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Allosteric inhibition of MALT1 in human OCI-LY3 cells assessed as reduction in BCL10 cleavage measured after 24 hrs by ELISA				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01245 BindingDB Entry DOI: 10.7270/Q2S1864D
					More data for this Ligand-Target Pair