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SMILES: COc1ccc(Oc2ccc(\C=C3/SC(=O)N(C3=O)c3ccc(OCCCCCN4CCN(C)CC4)cc3)cc2)cc1

InChI Key:

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50550918   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Inhibitor of nuclear factor kappa-B kinase subunit beta


(Homo sapiens (Human))		BDBM50550918
PNG
(CHEMBL4748753)
Show SMILES COc1ccc(Oc2ccc(\C=C3/SC(=O)N(C3=O)c3ccc(OCCCCCN4CCN(C)CC4)cc3)cc2)cc1
PDB

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n/an/a 700n/an/an/an/an/an/a


TBA

Assay Description
Allosteric inhibition of IKKbeta (unknown origin) using 5FAM-GRHDSGLDSMK-NH2 as substrate pretreated for 10 mins followed measured after 2 hrs by TR-...

Citation and Details

Article DOI: 10.1016/j.ejmech.2019.111955
BindingDB Entry DOI: 10.7270/Q2MS3XCC
More data for this
Ligand-Target Pair