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SMILES: Fc1cccc2nc([C@@H]3CC4(CC4)CN3c3ncnc4[nH]cnc34)n(C3CCCCC3)c(=O)c12

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50551253   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform


(Homo sapiens (Human))
BDBM50551253
PNG
(CHEMBL4742899)
Show SMILES Fc1cccc2nc([C@@H]3CC4(CC4)CN3c3ncnc4[nH]cnc34)n(C3CCCCC3)c(=O)c12 |r|
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 444n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human full-length recombinant His-tagged PI3K p110delta/p85alpha expressed in baculovirus expression system using PIP2 as substrate mea...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112143
BindingDB Entry DOI: 10.7270/Q28D00WW
More data for this
Ligand-Target Pair