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SMILES: Fc1ccc2cc(sc2c1)S(=O)(=O)N[C@H]1CCN(CCCc2noc3ccccc23)C1

InChI Key:

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50551368   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))
BDBM50551368
PNG
(CHEMBL4762226)
Show SMILES Fc1ccc2cc(sc2c1)S(=O)(=O)N[C@H]1CCN(CCCc2noc3ccccc23)C1 |r|
PDB
MMDB

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KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
1.10n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-ketanserin from recombinant human 5HT2A receptor expressed in CHOK1 cell membranes measured after 1 hr by microbeta counting met...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112149
BindingDB Entry DOI: 10.7270/Q2GX4G68
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50551368
PNG
(CHEMBL4762226)
Show SMILES Fc1ccc2cc(sc2c1)S(=O)(=O)N[C@H]1CCN(CCCc2noc3ccccc23)C1 |r|
PDB

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UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
18n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-methylspiperone from recombinant human D2 receptor expressed in CHOK1 cell membranes measured after 60 mins by microbeta countin...


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112149
BindingDB Entry DOI: 10.7270/Q2GX4G68
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50551368
PNG
(CHEMBL4762226)
Show SMILES Fc1ccc2cc(sc2c1)S(=O)(=O)N[C@H]1CCN(CCCc2noc3ccccc23)C1 |r|
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
38n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-LSD from recombinant human 5HT6 receptor expressed in CHOK1 cell membranes measured after 1 hr by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112149
BindingDB Entry DOI: 10.7270/Q2GX4G68
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50551368
PNG
(CHEMBL4762226)
Show SMILES Fc1ccc2cc(sc2c1)S(=O)(=O)N[C@H]1CCN(CCCc2noc3ccccc23)C1 |r|
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
93n/an/an/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-LSD from recombinant human 5HT7 receptor expressed in CHOK1 cell membranes measured after 120 mins by microbeta counting method


Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112149
BindingDB Entry DOI: 10.7270/Q2GX4G68
More data for this
Ligand-Target Pair