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SMILES: CCOC(=O)c1cnc2c(OC)cccc2c1-c1ccc(nc1)-c1ccccc1OC

InChI Key:

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50553630   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 7


(Rattus norvegicus (Rat))		BDBM50553630
PNG
(CHEMBL4758459)
Show SMILES CCOC(=O)c1cnc2c(OC)cccc2c1-c1ccc(nc1)-c1ccccc1OC
PDB

UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 600n/an/an/an/an/an/a


TBA

Assay Description
Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...

Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127529
BindingDB Entry DOI: 10.7270/Q28K7DQ0
More data for this
Ligand-Target Pair