null

SMILES: O=c1n(Cc2ccccc2)cnc2ccc(cc12)-c1ccncc1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50554261   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-adrenergic receptor kinase 1 (Homo sapiens (Human))	BDBM50554261 (CHEMBL4742242) Show SMILES O=c1n(Cc2ccccc2)cnc2ccc(cc12)-c1ccncc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human GRK2 by transcreener assay				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127602 BindingDB Entry DOI: 10.7270/Q2H135PS
					More data for this Ligand-Target Pair
G protein-coupled receptor kinase 5 (Homo sapiens (Human))	BDBM50554261 (CHEMBL4742242) Show SMILES O=c1n(Cc2ccccc2)cnc2ccc(cc12)-c1ccncc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	>8.33E+4	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to GRK5 (unknown origin) by Thermofluor thermal shift assay				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127602 BindingDB Entry DOI: 10.7270/Q2H135PS
					More data for this Ligand-Target Pair
Rhodopsin kinase GRK1 (Homo sapiens (Human))	BDBM50554261 (CHEMBL4742242) Show SMILES O=c1n(Cc2ccccc2)cnc2ccc(cc12)-c1ccncc1 Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	>8.33E+4	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to GRK1 (unknown origin) by Thermofluor thermal shift assay				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127602 BindingDB Entry DOI: 10.7270/Q2H135PS
					More data for this Ligand-Target Pair