null
SMILES: CN1C(=O)CCC(N2C(=O)c3cccc(NCCOCCC(=O)N4CCN(CC4)c4cccc(n4)-c4cnc5ccc(nn45)N4CCC[C@@H]4c4cccc(F)c4)c3C2=O)C1=O
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
BDNF/NT-3 growth factors receptor (Homo sapiens (Human)) | BDBM50554333 (CHEMBL4790500) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to human partial length TRKB expressed in mammalian expression system by kinomescan method | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01342 BindingDB Entry DOI: 10.7270/Q2KS6W6J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM50554333 (CHEMBL4790500) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 0.880 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to human partial length TRKA expressed in mammalian expression system by kinomescan method | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01342 BindingDB Entry DOI: 10.7270/Q2KS6W6J | |||||||||||
More data for this Ligand-Target Pair |