null

SMILES: CC(c1nnc2sc(nn12)-c1cnn(C)c1)c1ccc2ncccc2c1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50557861   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50557861 (CHEMBL4762193) Show SMILES CC(c1nnc2sc(nn12)-c1cnn(C)c1)c1ccc2ncccc2c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of c-Met (unknown origin) using poly Glu-Tyr as substrate preincubated for 10 mins followed by ATP addition by phosphoenolpyruvate/pyruvat...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00094 BindingDB Entry DOI: 10.7270/Q28919JG
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50557861 (CHEMBL4762193) Show SMILES CC(c1nnc2sc(nn12)-c1cnn(C)c1)c1ccc2ncccc2c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of c-MET in human SNU-5 cells measured after 6 hrs by steady-glo luciferase reporter gene assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00094 BindingDB Entry DOI: 10.7270/Q28919JG
					More data for this Ligand-Target Pair