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SMILES: CCNC(=O)Nc1ccc(cc1)S(=O)(=O)Oc1ccccc1CC

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50559136   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dihydroorotate dehydrogenase (quinone), mitochondrial


(Homo sapiens (Human))
BDBM50559136
PNG
(CHEMBL2165736)
Show SMILES CCNC(=O)Nc1ccc(cc1)S(=O)(=O)Oc1ccccc1CC
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 72n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant N-terminal His-tagged human DHODH (31 to 395 residues) expressed in Escherichia coli using L-DHO as substrate measured ever...


Citation and Details

Article DOI: 10.1016/j.bmc.2020.115739
BindingDB Entry DOI: 10.7270/Q29K4FX8
More data for this
Ligand-Target Pair