null
SMILES: CC(C)OP(=O)(OCC#C)C(Cc1cc(nc(c1)C(C)(C)C)C(C)(C)C)P(=O)(OC(C)C)OC(C)C
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3-hydroxy-3-methylglutaryl-coenzyme A reductase (Homo sapiens (Human)) | BDBM50559948 (CHEMBL4797059) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 633 | n/a | n/a | n/a | n/a |
TBA | Assay Description Induction of degradation of Flag-tagged human HMGCR-dCat-ELuc membrane domain (1 to 499 residues) expressed in HEK293 cells assessed as reduction in ... | Citation and Details Article DOI: 10.1016/j.bmc.2020.115576 BindingDB Entry DOI: 10.7270/Q2988BQR | |||||||||||
More data for this Ligand-Target Pair |