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SMILES: COc1cccc2N(C)C3N(CCc4c3[nH]c3ccccc43)C(=O)c12

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50560848   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' (Homo sapiens (Human))	BDBM50560848 (4-Methoxyevodiamine | CHEMBL2171791) Show SMILES COc1cccc2N(C)C3N(CCc4c3[nH]c3ccccc43)C(=O)c12 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human PDE6C (2-854 residues) expressed in Sf9 cells incubated for 15 mins using [3H]-cGMP as substrate by liquid scintillation counting...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00983 BindingDB Entry DOI: 10.7270/Q2668HWF
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50560848 (4-Methoxyevodiamine | CHEMBL2171791) Show SMILES COc1cccc2N(C)C3N(CCc4c3[nH]c3ccccc43)C(=O)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human PDE5A1 (535-860 residues) expressed in Escherichia coli BL21 incubated for 15 mins using [3H]-cGMP as substrate by liquid scintil...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00983 BindingDB Entry DOI: 10.7270/Q2668HWF
					More data for this Ligand-Target Pair