null
SMILES: CC1Cc2[nH]c3c(F)ccc(C)c3c2CN1C(=O)c1cc([nH]n1)C(F)(F)F
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human)) | BDBM50561354 (CHEMBL4784101) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 22 | n/a | n/a | n/a | n/a |
TBA | Assay Description Potentiation of human CFTR F508 deletion mutant expressed in rat FRT cells coexpressing HS-YFP assessed as increase in iodide influx pre-incubated fo... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01050 BindingDB Entry DOI: 10.7270/Q2639TFP | |||||||||||
More data for this Ligand-Target Pair |