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SMILES: Cc1[nH]c2ccc(cc2c1C)C(=O)N1CCN(Cc2ccc3OCOc3c2)CC1

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50561416   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Orexin/Hypocretin receptor type 1


(Homo sapiens (Human))		BDBM50561416
PNG
(CHEMBL4794519)
Show SMILES Cc1[nH]c2ccc(cc2c1C)C(=O)N1CCN(Cc2ccc3OCOc3c2)CC1
PDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-SB67404 from human orexin 1 receptor expressed in CHO cells incubated for 2 hrs by whole cell radioligand binding assay

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c00964
BindingDB Entry DOI: 10.7270/Q2XK8K72
More data for this
Ligand-Target Pair