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SMILES: Cc1ccc(cc1Cl)-n1c(cc2cccnc12)C(=O)NC1CCC1

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50561540   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50561540
PNG
(CHEMBL4790633)
Show SMILES Cc1ccc(cc1Cl)-n1c(cc2cccnc12)C(=O)NC1CCC1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.30E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...

Citation and Details

Article DOI: 10.1021/acsmedchemlett.9b00369
BindingDB Entry DOI: 10.7270/Q2WM1J4P
More data for this
Ligand-Target Pair