BindingDB logo
myBDB logout

null

SMILES: Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CN2CCC3(C2)CCNCC3)[C@@H](O)[C@H]1O

InChI Key:

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50561810   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Methylosome protein 50/Protein arginine N-methyltransferase 5


(Homo sapiens (Human))		BDBM50561810
PNG
(CHEMBL4778043)
Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CN2CCC3(C2)CCNCC3)[C@@H](O)[C@H]1O |r|
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.40E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of full-length human N-terminal FLAG-tagged PRMT5/full length N-terminal His6-tagged MEP50 (unknown origin) expressed in baculovirus infec...

Citation and Details

Article DOI: 10.1021/acsmedchemlett.0c00355
BindingDB Entry DOI: 10.7270/Q2RR22Z5
More data for this
Ligand-Target Pair