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Enter Data

null

SMILES: COc1cn(ccc1=O)-c1ccc(OCCCN2CCCC2)cc1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50562729
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50562729 (CHEMBL4748265) Show SMILES COc1cn(ccc1=O)-c1ccc(OCCCN2CCCC2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.520	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human histamine H3 receptor expressed in HEK293 cells preincubated for 5 mins followed by forskolin-stimulation and measured a...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.113096 BindingDB Entry DOI: 10.7270/Q2T72N5B
TBA					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50562729 (CHEMBL4748265) Show SMILES COc1cn(ccc1=O)-c1ccc(OCCCN2CCCC2)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human histamine H4 receptor expressed in HEK293 cells preincubated for 5 mins followed by forskolin-stimulation and measured a...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.113096 BindingDB Entry DOI: 10.7270/Q2T72N5B
TBA					More data for this Ligand-Target Pair
Histamine H2 receptor (Homo sapiens (Human))	BDBM50562729 (CHEMBL4748265) Show SMILES COc1cn(ccc1=O)-c1ccc(OCCCN2CCCC2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human histamine H2 receptor expressed in HEK293 cells preincubated for 5 mins followed by forskolin-stimulation and measured a...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.113096 BindingDB Entry DOI: 10.7270/Q2T72N5B
TBA					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50562729 (CHEMBL4748265) Show SMILES COc1cn(ccc1=O)-c1ccc(OCCCN2CCCC2)cc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human histamine H1 receptor expressed in HEK293 cells preincubated for 5 mins followed by forskolin-stimulation and measured a...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.113096 BindingDB Entry DOI: 10.7270/Q2T72N5B
TBA					More data for this Ligand-Target Pair