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null

SMILES: O\N=C\c1cc(Cl)cc(CN2CCN(CC2)c2ccncc2)c1O

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50563465
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Acetylcholinesterase (Homo sapiens (Human))	BDBM50563465 (CHEMBL4758307) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.62E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human AChE assessed as decrease in enzyme activity incubated for 30 mins by Ellman's method				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113286 BindingDB Entry DOI: 10.7270/Q2ZP49VN
TBA					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50563465 (CHEMBL4758307) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Reactivation of sarin-inhibited human AChE assessed as dissociation constant incubated for 30 mins by Ellman's method				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113286 BindingDB Entry DOI: 10.7270/Q2ZP49VN
TBA					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50563465 (CHEMBL4758307) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.33E+4	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Reactivation of VX-inhibited human AChE assessed as dissociation constant incubated for 30 mins by Ellman's method				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113286 BindingDB Entry DOI: 10.7270/Q2ZP49VN
TBA					More data for this Ligand-Target Pair