null

SMILES: COc1cc(ccc1CS(=O)(=O)Nc1ccc2n(C)c(=O)c(C)cc2c1)C(=O)NO

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50564929   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peregrin (Homo sapiens (Human))	BDBM50564929 (CHEMBL4784767) Show SMILES COc1cc(ccc1CS(=O)(=O)Nc1ccc2n(C)c(=O)c(C)cc2c1)C(=O)NO Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.58E+3	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to BRPF1 (unknown origin) by Isothermal titration calorimetry				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112338 BindingDB Entry DOI: 10.7270/Q2VD7363
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50564929 (CHEMBL4784767) Show SMILES COc1cc(ccc1CS(=O)(=O)Nc1ccc2n(C)c(=O)c(C)cc2c1)C(=O)NO Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	231	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant HDAC8 using H2N-Arg-His-Lys(Ac)-Lys(Ac)-AMC as substrate after 90 mins by fluorescence based micro plate assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112338 BindingDB Entry DOI: 10.7270/Q2VD7363
					More data for this Ligand-Target Pair