BindingDB PrimarySearch

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SMILES: C[C@@H](Nc1ccc2[nH]nc(\C=C\c3ccccn3)c2c1)c1cc(F)cc(F)c1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 23 hits for monomerid = 50565310
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50565310 (CHEMBL4792981) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
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NT-3 growth factor receptor (Homo sapiens (Human))	BDBM50565310 (CHEMBL4792981) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem	n/a	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a
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NT-3 growth factor receptor (Homo sapiens (Human))	BDBM50565310 (CHEMBL4792981) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
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ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50565310 (CHEMBL4792981) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem	n/a	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a
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NUAK family SNF1-like kinase 1 (Homo sapiens (Human))	BDBM50565310 (CHEMBL4792981) Show SMILES Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a
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Aurora kinase C (Homo sapiens (Human))	BDBM50565310 (CHEMBL4792981) Show SMILES Show InChI	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem	n/a	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a
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Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50565310 (CHEMBL4792981) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50565310 (CHEMBL4792981) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem	n/a	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50565310 (CHEMBL4792981) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a
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Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50565310 (CHEMBL4792981) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem	n/a	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM50565310 (CHEMBL4792981) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem	n/a	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50565310 (CHEMBL4792981) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50565310 (CHEMBL4792981) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem	n/a	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50565310 (CHEMBL4792981) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem	n/a	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a
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Muscle, skeletal receptor tyrosine-protein kinase (Homo sapiens (Human))	BDBM50565310 (CHEMBL4792981) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a
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Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (Homo sapiens (Human))	BDBM50565310 (CHEMBL4792981) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM50565310 (CHEMBL4792981) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase ROS (Homo sapiens (Human))	BDBM50565310 (CHEMBL4792981) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase receptor Tie-1 (Homo sapiens (Human))	BDBM50565310 (CHEMBL4792981) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem	n/a	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a
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Activated CDC42 kinase 1 (Homo sapiens (Human))	BDBM50565310 (CHEMBL4792981) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem	n/a	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a
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High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50565310 (CHEMBL4792981) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem	n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a
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BDNF/NT-3 growth factors receptor (Homo sapiens (Human))	BDBM50565310 (CHEMBL4792981) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem	n/a	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a
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BDNF/NT-3 growth factors receptor (Homo sapiens (Human))	BDBM50565310 (CHEMBL4792981) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
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