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SMILES: COC(=O)c1sccc1Nc1nc(Nc2ccc(cc2)N2CCC(O)CC2)ncc1[N+]([O-])=O

InChI Key:

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50565558   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase PLK1


(Homo sapiens (Human))		BDBM50565558
PNG
(CHEMBL4783888)
Show SMILES COC(=O)c1sccc1Nc1nc(Nc2ccc(cc2)N2CCC(O)CC2)ncc1[N+]([O-])=O
PDB
MMDB

NCI pathway
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KEGG

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.30n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human PLK1 using casein as substrate in presence of [gamma-33P]ATP by radiometric assay

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112697
BindingDB Entry DOI: 10.7270/Q2PK0KWC
More data for this
Ligand-Target Pair