null

SMILES: CC1CCN(CC1)c1nc(ccc1CNC(=O)Nc1ccc2ccc(=O)[nH]c2c1)C(F)(F)F

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50566149   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50566149 (CHEMBL4783554) Show SMILES CC1CCN(CC1)c1nc(ccc1CNC(=O)Nc1ccc2ccc(=O)[nH]c2c1)C(F)(F)F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.830	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of 30 nM capsaicin-induced calcium uptake				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00982 BindingDB Entry DOI: 10.7270/Q2X06BSQ
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50566149 (CHEMBL4783554) Show SMILES CC1CCN(CC1)c1nc(ccc1CNC(=O)Nc1ccc2ccc(=O)[nH]c2c1)C(F)(F)F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]RTX from human TRPV1 expressed in CHO cells				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00982 BindingDB Entry DOI: 10.7270/Q2X06BSQ
					More data for this Ligand-Target Pair