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SMILES: Cc1c(N2CCC(C2)C2(N)CC2)c(F)cc2c(cc(=O)n(C3CC3)c12)-c1n[nH]c(=O)o1

InChI Key:

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50566546   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Potassium voltage-gated channel subfamily H member 2


(Homo sapiens (Human))		BDBM50566546
PNG
(CHEMBL4875871)
Show SMILES Cc1c(N2CCC(C2)C2(N)CC2)c(F)cc2c(cc(=O)n(C3CC3)c12)-c1n[nH]c(=O)o1
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PC cid
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PubMed
n/an/a 1.30E+4n/an/an/an/an/an/a


TBA

Assay Description
Displacement of [3H]-dofetilide from human ERG after 60 mins by scintillation counting method

Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00375
BindingDB Entry DOI: 10.7270/Q2KH0S2G
More data for this
Ligand-Target Pair