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SMILES: Oc1cccc(c1)-n1cnc2cnc(Nc3cc(F)c(O)c(F)c3)nc12

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50568109   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM50568109 (CHEMBL4861235 | US11851436, Compound A1-10) Show SMILES Oc1cccc(c1)-n1cnc2cnc(Nc3cc(F)c(O)c(F)c3)nc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	95.8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM50568109 (CHEMBL4861235 | US11851436, Compound A1-10) Show SMILES Oc1cccc(c1)-n1cnc2cnc(Nc3cc(F)c(O)c(F)c3)nc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RSK2 (unknown origin) using Ulight-rpS6 as substrate incubated for 1 hr in presence of ATP by TR FRET assay				Citation and Details Article DOI: 10.1016/j.bmc.2021.116220 BindingDB Entry DOI: 10.7270/Q2H70KKB
					More data for this Ligand-Target Pair