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SMILES: Cn1c2nc(Nc3cccc(c3)S(C)(=O)=O)ncc2cc(-c2ccc(F)cc2Cl)c1=O

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50568947   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM50568947 (CHEMBL4867716) Show SMILES Cn1c2nc(Nc3cccc(c3)S(C)(=O)=O)ncc2cc(-c2ccc(F)cc2Cl)c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	218	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113252 BindingDB Entry DOI: 10.7270/Q21Z4863
					More data for this Ligand-Target Pair
Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50568947 (CHEMBL4867716) Show SMILES Cn1c2nc(Nc3cccc(c3)S(C)(=O)=O)ncc2cc(-c2ccc(F)cc2Cl)c1=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant RIPK2 (unknown origin) using RS repeat peptide as substrate preincubated for 5 mins followed by substrate and ATP addition ...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113252 BindingDB Entry DOI: 10.7270/Q21Z4863
					More data for this Ligand-Target Pair