BindingDB PrimarySearch_ki

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Enter Data

null

SMILES: CN1CCC(=CC1)C1=Nc2cc(F)ccc2Nc2ccc(Cl)cc12

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50569117
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50569117 (CHEMBL4875709) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	108	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human D2 receptor expressed in CHO cells assessed as inhibition of dopamine-induced calcium accumulation				Citation and Details Article DOI: 10.1016/j.bmcl.2021.127911 BindingDB Entry DOI: 10.7270/Q2C82F2T
TBA					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50569117 (CHEMBL4875709) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at muscarinic M1 receptor (unknown origin) expressed in CHO cells				Citation and Details Article DOI: 10.1016/j.bmcl.2021.127911 BindingDB Entry DOI: 10.7270/Q2C82F2T
TBA					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50569117 (CHEMBL4875709) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at muscarinic M4 receptor (unknown origin) expressed in CHO cells				Citation and Details Article DOI: 10.1016/j.bmcl.2021.127911 BindingDB Entry DOI: 10.7270/Q2C82F2T
TBA					More data for this Ligand-Target Pair