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SMILES: COc1cc2CCN(Cc2cc1OC)C(=O)c1ccc(o1)-c1ccc2OCOc2c1

InChI Key:

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50569185   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50569185
PNG
(CHEMBL4856166)
Show SMILES COc1cc2CCN(Cc2cc1OC)C(=O)c1ccc(o1)-c1ccc2OCOc2c1
PDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 8.40E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of P-glycoprotein in human MCF7/ADR cells assessed as reversal fold by measuring reduction in doxorubicin IC50 at 5 uM incubated for 48 hr...

Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113336
BindingDB Entry DOI: 10.7270/Q2QF8XMW
More data for this
Ligand-Target Pair