Found 2 hits for monomerid = 50569298 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50569298
(CHEMBL4878395)Show SMILES O[C@@H](CNCCCCCCCCCOc1ccc(cc1)C(NC(=O)O[C@H]1CN2CCC1CC2)c1ccccc1)c1ccc(O)c2[nH]c(=O)ccc12 |r,wU:1.0,25.25,(3.18,-8.47,;4.52,-9.24,;5.85,-8.47,;7.19,-9.23,;8.52,-8.46,;9.85,-9.22,;11.18,-8.45,;12.52,-9.22,;13.85,-8.44,;15.19,-9.21,;16.52,-8.43,;17.85,-9.2,;19.19,-8.43,;20.52,-9.19,;21.85,-8.42,;23.19,-9.19,;24.52,-8.41,;24.51,-6.87,;23.17,-6.11,;21.84,-6.88,;25.84,-6.1,;27.18,-6.86,;28.51,-6.08,;28.5,-4.54,;29.85,-6.84,;31.18,-6.06,;31.17,-4.53,;32.5,-3.76,;33.84,-4.53,;33.84,-6.07,;32.52,-6.84,;33.21,-5.48,;31.73,-5.09,;25.84,-4.56,;27.17,-3.79,;27.16,-2.25,;25.82,-1.48,;24.49,-2.27,;24.5,-3.8,;4.52,-10.78,;3.19,-11.55,;3.19,-13.09,;4.53,-13.86,;4.53,-15.4,;5.86,-13.09,;7.19,-13.86,;8.53,-13.09,;9.86,-13.87,;8.53,-11.55,;7.19,-10.77,;5.86,-11.54,)| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 0.251 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Displacement of 125I-cyanopindolol from human adrenergic beta2 receptor |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127975 BindingDB Entry DOI: 10.7270/Q2F193HC |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(Homo sapiens (Human)) | BDBM50569298
(CHEMBL4878395)Show SMILES O[C@@H](CNCCCCCCCCCOc1ccc(cc1)C(NC(=O)O[C@H]1CN2CCC1CC2)c1ccccc1)c1ccc(O)c2[nH]c(=O)ccc12 |r,wU:1.0,25.25,(3.18,-8.47,;4.52,-9.24,;5.85,-8.47,;7.19,-9.23,;8.52,-8.46,;9.85,-9.22,;11.18,-8.45,;12.52,-9.22,;13.85,-8.44,;15.19,-9.21,;16.52,-8.43,;17.85,-9.2,;19.19,-8.43,;20.52,-9.19,;21.85,-8.42,;23.19,-9.19,;24.52,-8.41,;24.51,-6.87,;23.17,-6.11,;21.84,-6.88,;25.84,-6.1,;27.18,-6.86,;28.51,-6.08,;28.5,-4.54,;29.85,-6.84,;31.18,-6.06,;31.17,-4.53,;32.5,-3.76,;33.84,-4.53,;33.84,-6.07,;32.52,-6.84,;33.21,-5.48,;31.73,-5.09,;25.84,-4.56,;27.17,-3.79,;27.16,-2.25,;25.82,-1.48,;24.49,-2.27,;24.5,-3.8,;4.52,-10.78,;3.19,-11.55,;3.19,-13.09,;4.53,-13.86,;4.53,-15.4,;5.86,-13.09,;7.19,-13.86,;8.53,-13.09,;9.86,-13.87,;8.53,-11.55,;7.19,-10.77,;5.86,-11.54,)| | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Displacement of [3H]-N-methylscopolamine from human muscarinic M3 receptor |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.127975 BindingDB Entry DOI: 10.7270/Q2F193HC |
More data for this Ligand-Target Pair | |