null
SMILES: CCc1ccc(NCC(=O)NCc2ccc(cc2)S(N)(=O)=O)cc1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50572410 (CHEMBL4869520) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.440 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human CA2 pre-incubated for 15 mins measured by stopped flow CO2 hydration assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01889 BindingDB Entry DOI: 10.7270/Q2ZW1QQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 12 (Homo sapiens (Human)) | BDBM50572410 (CHEMBL4869520) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 73 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human CA12 pre-incubated for 15 mins measured by stopped flow CO2 hydration assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01889 BindingDB Entry DOI: 10.7270/Q2ZW1QQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50572410 (CHEMBL4869520) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 95 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human CA1 pre-incubated for 15 mins measured by stopped flow CO2 hydration assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01889 BindingDB Entry DOI: 10.7270/Q2ZW1QQR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 7 (Homo sapiens (Human)) | BDBM50572410 (CHEMBL4869520) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 218 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human CA7 pre-incubated for 15 mins measured by stopped flow CO2 hydration assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01889 BindingDB Entry DOI: 10.7270/Q2ZW1QQR | |||||||||||
More data for this Ligand-Target Pair |