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SMILES: CN(Cc1c(F)cccc1Cl)S(=O)(=O)N1CCc2cc(ccc2C1)N1CCN(CC1)C(C)=O

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50572708   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM50572708 (CHEMBL4851155) Show SMILES CN(Cc1c(F)cccc1Cl)S(=O)(=O)N1CCc2cc(ccc2C1)N1CCN(CC1)C(C)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	190	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human RORgammat LBD expressed in HEK293T cells incubated for 16 to 20 hrs by Gal4-luciferase reporter gene assay				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113585 BindingDB Entry DOI: 10.7270/Q2S75M5R
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Mus musculus)	BDBM50572708 (CHEMBL4851155) Show SMILES CN(Cc1c(F)cccc1Cl)S(=O)(=O)N1CCc2cc(ccc2C1)N1CCN(CC1)C(C)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	220	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at RORgammat in C57 mouse CD4+ T cells cells assessed as induction of Th17 cells differentiation by measuring increase in IL17 produ...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113585 BindingDB Entry DOI: 10.7270/Q2S75M5R
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM50572708 (CHEMBL4851155) Show SMILES CN(Cc1c(F)cccc1Cl)S(=O)(=O)N1CCc2cc(ccc2C1)N1CCN(CC1)C(C)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	21	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at europium-labeled human RORgammat LBD assessed as induction of XL665-labeled co-activator SRC1 recruitment incubated for 1 hr by d...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113585 BindingDB Entry DOI: 10.7270/Q2S75M5R
					More data for this Ligand-Target Pair