null

SMILES: Cn1ncc(Nc2ccc(CCN)cc2)c(Cl)c1=O

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50573197   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nucleosome-remodeling factor subunit BPTF (Homo sapiens (Human))	BDBM50573197 (CHEMBL4872300) Show SMILES Cn1ncc(Nc2ccc(CCN)cc2)c(Cl)c1=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of HIS9-tagged BPTF (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01294 BindingDB Entry DOI: 10.7270/Q2HM5D7G
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50573197 (CHEMBL4872300) Show SMILES Cn1ncc(Nc2ccc(CCN)cc2)c(Cl)c1=O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of HIS9-tagged BRD4 (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by AlphaScreen assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01294 BindingDB Entry DOI: 10.7270/Q2HM5D7G
					More data for this Ligand-Target Pair
Nucleosome-remodeling factor subunit BPTF (Homo sapiens (Human))	BDBM50573197 (CHEMBL4872300) Show SMILES Cn1ncc(Nc2ccc(CCN)cc2)c(Cl)c1=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to BPTF (unknown origin) by by BROMOscan method				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01294 BindingDB Entry DOI: 10.7270/Q2HM5D7G
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50573197 (CHEMBL4872300) Show SMILES Cn1ncc(Nc2ccc(CCN)cc2)c(Cl)c1=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to PCAF (unknown origin) by BROMOscan method				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01294 BindingDB Entry DOI: 10.7270/Q2HM5D7G
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50573197 (CHEMBL4872300) Show SMILES Cn1ncc(Nc2ccc(CCN)cc2)c(Cl)c1=O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to BRD4 BD1 (unknown origin) by BROMOscan method				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01294 BindingDB Entry DOI: 10.7270/Q2HM5D7G
					More data for this Ligand-Target Pair
Chromatin remodeling regulator CECR2 (Homo sapiens (Human))	BDBM50573197 (CHEMBL4872300) Show SMILES Cn1ncc(Nc2ccc(CCN)cc2)c(Cl)c1=O Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to CECR2 (unknown origin) by BROMOscan method				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01294 BindingDB Entry DOI: 10.7270/Q2HM5D7G
					More data for this Ligand-Target Pair
Bromodomain-containing protein 7 (Homo sapiens (Human))	BDBM50573197 (CHEMBL4872300) Show SMILES Cn1ncc(Nc2ccc(CCN)cc2)c(Cl)c1=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.760	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to BRD7 (unknown origin) by BROMOscan method				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01294 BindingDB Entry DOI: 10.7270/Q2HM5D7G
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 (Homo sapiens (Human))	BDBM50573197 (CHEMBL4872300) Show SMILES Cn1ncc(Nc2ccc(CCN)cc2)c(Cl)c1=O Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.470	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to BRD9 (unknown origin) by BROMOscan method				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01294 BindingDB Entry DOI: 10.7270/Q2HM5D7G
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2A (Homo sapiens (Human))	BDBM50573197 (CHEMBL4872300) Show SMILES Cn1ncc(Nc2ccc(CCN)cc2)c(Cl)c1=O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to GCN5L2 (unknown origin) by BROMOscan method				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01294 BindingDB Entry DOI: 10.7270/Q2HM5D7G
					More data for this Ligand-Target Pair