null
SMILES: Oc1cccc(CNc2nc(cc(n2)C(F)(F)F)-c2ccco2)c1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50574118 (CHEMBL4878029) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Negative modulator activity at human TLR8 expressed in HEK-Blue hTLR8 cells assessed as inhibition of TL8-506 stimulated NF-kappaB activation preincu... | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113809 BindingDB Entry DOI: 10.7270/Q2J67MRM | |||||||||||
More data for this Ligand-Target Pair |