null

SMILES: [H][C@@]12CCC(C(C)(O)CCCCCCOCCOCCOCc3cn(CCOCCOCCOCCOCCOCCS(=O)(=O)c4ccc(C(=O)Nc5ccc(Cl)c(c5)-c5ccccn5)c(Cl)c4)nn3)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@@H](O)CC[C@]12C

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50574140   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Smoothened homolog (Mus musculus)	BDBM50574140 (CHEMBL4848651) Show SMILES [H][C@@]12CCC(C(C)(O)CCCCCCOCCOCCOCc3cn(CCOCCOCCOCCOCCOCCS(=O)(=O)c4ccc(C(=O)Nc5ccc(Cl)c(c5)-c5ccccn5)c(Cl)c4)nn3)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@@H](O)CC[C@]12C |r,t:85| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at SMO in mouse NIH3T3 cells preincubated for 2 hrs followed by SAG stimulation and measured after 24 hrs by Bright-Glo luciferas...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01220 BindingDB Entry DOI: 10.7270/Q2DJ5KFM
					More data for this Ligand-Target Pair