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Enter Data

null

SMILES: CC(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50574242
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Melanocortin receptor 3 (Mus musculus)	BDBM50574242 (CHEMBL4859395) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01417 BindingDB Entry DOI: 10.7270/Q2RR231G
TBA					More data for this Ligand-Target Pair
Melanocortin receptor 3 (Mus musculus)	BDBM50574242 (CHEMBL4859395) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	790	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at mouse melanocortin receptor 3 expressed in HEK293 cells assessed as inhibition of NDP-MSH-induced cAMP accumulation incubated ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01417 BindingDB Entry DOI: 10.7270/Q2RR231G
TBA					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Mus musculus)	BDBM50574242 (CHEMBL4859395) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at mouse MC4R expressed in HEK293 cells assessed as induction of cAMP level incubated for 2 hr by alphaScreen assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01417 BindingDB Entry DOI: 10.7270/Q2RR231G
TBA					More data for this Ligand-Target Pair
Melanocortin receptor 3 (Mus musculus)	BDBM50574242 (CHEMBL4859395) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at mouse MC3R expressed in HEK293 cells assessed as induction of cAMP level incubated for 2 hr by alphaScreen assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01417 BindingDB Entry DOI: 10.7270/Q2RR231G
TBA					More data for this Ligand-Target Pair
Melanocyte-stimulating hormone receptor (Mus musculus)	BDBM50574242 (CHEMBL4859395) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Partial agonist activity at mouse MC1R expressed in HEK293 cells assessed as induction of cAMP level incubated for 2 hr by alphaScreen assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01417 BindingDB Entry DOI: 10.7270/Q2RR231G
TBA					More data for this Ligand-Target Pair
Melanocortin receptor 5 (Mus musculus (Mouse))	BDBM50574242 (CHEMBL4859395) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at mouse MC5R expressed in HEK293 cells assessed as induction of cAMP level at 100 uM incubated for 2 hr by alphaScreen assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01417 BindingDB Entry DOI: 10.7270/Q2RR231G
TBA					More data for this Ligand-Target Pair