null

SMILES: Fc1ccc2OCCc2c1CNc1ncc(N2CC3(CC3)CC2=O)c2nncn12

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50575274   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polycomb protein EED (Homo sapiens (Human))	BDBM50575274 (CHEMBL4856933) Show SMILES Fc1ccc2OCCc2c1CNc1ncc(N2CC3(CC3)CC2=O)c2nncn12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50575274 (CHEMBL4856933) Show SMILES Fc1ccc2OCCc2c1CNc1ncc(N2CC3(CC3)CC2=O)c2nncn12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair