BindingDB logo
myBDB logout

null

SMILES: COc1cc(ccc1Nc1ncc2C(OC(=O)N(c3cccc(NC(=O)C=C)c3)c2n1)C(C)C)N1CCN(C)CC1

InChI Key:

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50578025   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ribosomal protein S6 kinase alpha-6


(Homo sapiens (Human))		BDBM50578025
PNG
(CHEMBL4865220)
Show SMILES COc1cc(ccc1Nc1ncc2C(OC(=O)N(c3cccc(NC(=O)C=C)c3)c2n1)C(C)C)N1CCN(C)CC1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.12E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of RSK4 (unknown origin) incubated for 40 mins in presence of ATP and lipid substrate by Kinase-Glo plus luminescence assay

Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00969
BindingDB Entry DOI: 10.7270/Q2WD44DC
More data for this
Ligand-Target Pair