null
SMILES: [H][C@@]12CC[C@@H](C)[C@]3([H])CC[C@@]4(C)OO[C@@]13[C@]([H])(O[C@H](OC[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NC(\C=C\P(=O)(OCC)OCC)c1ccccc1)[C@@H]2C)O4
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cysteine proteinase falcipain 2a (Plasmodium falciparum) | BDBM50578405 (CHEMBL4856045) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.49E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant Plasmodium falciparum falcipain-2 expressed in Escherichia coli M15 assessed as reduction in free AMC release using Z-FR-AM... | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113454 BindingDB Entry DOI: 10.7270/Q25T3Q99 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cysteine proteinase falcipain 2a (Plasmodium falciparum) | BDBM50578405 (CHEMBL4856045) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant Plasmodium falciparum falcipain-2 expressed in Escherichia coli M15 assessed as reduction in free AMC release using Z-FR-AM... | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113454 BindingDB Entry DOI: 10.7270/Q25T3Q99 | |||||||||||
More data for this Ligand-Target Pair |