BindingDB PrimarySearch

null

SMILES: COC1=C(Cc2ccc(s2)-c2cn(Cc3ccccc3)cc(C(O)=O)c2=O)C(=O)N(C1)c1ccc2ccccc2c1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50579801
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histone acetyltransferase p300 (Homo sapiens (Human))	BDBM50579801 (CHEMBL5088992) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EP300 (unknown origin) by AlphaLISA immunodetection assay				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128358 BindingDB Entry DOI: 10.7270/Q23R0XQQ
TBA					More data for this Ligand-Target Pair
CREB-binding protein (Homo sapiens (Human))	BDBM50579801 (CHEMBL5088992) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CBP (unknown origin)				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128358 BindingDB Entry DOI: 10.7270/Q23R0XQQ
TBA					More data for this Ligand-Target Pair
Histone acetyltransferase KAT7 (Homo sapiens)	BDBM50579801 (CHEMBL5088992) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of MYST2 (unknown origin)				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128358 BindingDB Entry DOI: 10.7270/Q23R0XQQ
TBA					More data for this Ligand-Target Pair
Histone acetyltransferase KAT5 (Homo sapiens (Human))	BDBM50579801 (CHEMBL5088992) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of TIP60 (unknown origin)				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128358 BindingDB Entry DOI: 10.7270/Q23R0XQQ
TBA					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50579801 (CHEMBL5088992) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PCAF (unknown origin)				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128358 BindingDB Entry DOI: 10.7270/Q23R0XQQ
TBA					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2A (Homo sapiens (Human))	BDBM50579801 (CHEMBL5088992) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GCN5 (unknown origin)				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128358 BindingDB Entry DOI: 10.7270/Q23R0XQQ
TBA					More data for this Ligand-Target Pair
Histone acetyltransferase KAT6B (Homo sapiens)	BDBM50579801 (CHEMBL5088992) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of MYST4 (unknown origin)				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128358 BindingDB Entry DOI: 10.7270/Q23R0XQQ
TBA					More data for this Ligand-Target Pair