null

SMILES: F\C(CNC(=O)NS(=O)(=O)c1cc(Cl)c(Cl)s1)=C1\CCCc2cnn(Cc3ccc(Cl)cc3Cl)c12

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50580032   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50580032 (CHEMBL5078847) Show SMILES F\C(CNC(=O)NS(=O)(=O)c1cc(Cl)c(Cl)s1)=C1\CCCc2cnn(Cc3ccc(Cl)cc3Cl)c12 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-PGE2 from human EP3 receptor assessed as inhibition constant incubated for 2 hrs by TopCount scintillation counting method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00594 BindingDB Entry DOI: 10.7270/Q2HT2T6X
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50580032 (CHEMBL5078847) Show SMILES F\C(CNC(=O)NS(=O)(=O)c1cc(Cl)c(Cl)s1)=C1\CCCc2cnn(Cc3ccc(Cl)cc3Cl)c12 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human EP3 receptor expressed in CHO-K1 cells assessed as reduction in sulprostone induced inhibition of forskolin stimulated c...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00594 BindingDB Entry DOI: 10.7270/Q2HT2T6X
					More data for this Ligand-Target Pair