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SMILES: COc1cc(ccc1OCCCCc1ccnc(N)c1)N(C1CCC1)C(=S)NCCCn1cncc1C

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50581398   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutaminyl-peptide cyclotransferase


(Homo sapiens (Human))		BDBM50581398
PNG
(CHEMBL5083519)
Show SMILES COc1cc(ccc1OCCCCc1ccnc(N)c1)N(C1CCC1)C(=S)NCCCn1cncc1C
PDB
MMDB

KEGG

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antibodypedia
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.800n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry

Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113819
BindingDB Entry DOI: 10.7270/Q2M61Q44
More data for this
Ligand-Target Pair