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SMILES: C[C@H](Oc1cc(c(F)cc1C(=O)Nc1c(F)cccc1Cl)-c1ccc2CCCNc2n1)C(F)(F)F

InChI Key:

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50581626   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dihydroorotate dehydrogenase (quinone), mitochondrial


(Homo sapiens (Human))		BDBM50581626
PNG
(CHEMBL5092899)
Show SMILES C[C@H](Oc1cc(c(F)cc1C(=O)Nc1c(F)cccc1Cl)-c1ccc2CCCNc2n1)C(F)(F)F |r|
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PC cid
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Article
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n/an/a 0.202n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human DHODH using dihydroorotate as substrate and CoQ6 as co-substrate by DCIP dye based spectrophotometry analysis

Citation and Details

Article DOI: 10.1021/acsmedchemlett.2c00017
BindingDB Entry DOI: 10.7270/Q2SQ948N
More data for this
Ligand-Target Pair