BindingDB PrimarySearch_ki

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null

SMILES: O=C(NCCN1CCCCC1)c1cccn2c1nc1c3ccccc3ccc1c2=O

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50582299
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cytochrome P450 1A2 (Homo sapiens (Human))	BDBM50582299 (CHEMBL5091051) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human hepatic CYP1A2 expressed in baculovirus insect cell expression system in presence of CEC substrate measured by fluore...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50582299 (CHEMBL5091051) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition on hERG expressed in HEK293 cells by Qpatch method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human))	BDBM50582299 (CHEMBL5091051) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW
TBA					More data for this Ligand-Target Pair