null
SMILES: OC1(O)CCN(CCNC(=O)c2cccn3c2nc2cc4ccccc4cc2c3=O)CC1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human)) | BDBM50582320 (CHEMBL5089364) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW | |||||||||||
More data for this Ligand-Target Pair |